Nucleus accumbens dopamine modulates response rate but not response timing in an interval timing task.
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چکیده
منابع مشابه
Nucleus accumbens dopamine modulates response rate but not response timing in an interval timing task.
While previous work has demonstrated that systemic dopamine manipulations can modulate temporal perception by altering the speed of internal clock processes, the neural site of this modulation remains unclear. Based on recent research suggesting that changes in incentive salience can alter the perception of time, as well as work showing that nucleus accumbens (NAc) shell dopamine (DA) levels mo...
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BACKGROUND It is well known that brain dopamine (DA) signals support risk-based decision making; however, the specific terminal regions of midbrain DA neurons through which DA signals mediate risk-based decision making are unknown. METHODS Using microinfusions of the D1/D2 receptor antagonist flupenthixol, we sought to explore the role of D1/D2 receptor activity in the rat orbitofrontal corte...
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The nucleus accumbens is a brain region in which limbic and motor inputs converge. How these information modalities shape accumbens output is not clearly understood. Here, we report that synaptic inputs from the prefrontal cortex and limbic structures interact differently depending on their timing. Coincident inputs may result in enhancing information flow through the nucleus accumbens. Respons...
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Matthew T. Kaufman, Jeffrey S. Seely, David Sussillo, Stephen I. Ryu, Krishna V. Shenoy and Mark M. Churchland Neurosciences Program, Stanford University, Stanford, CA 94305 Department of Electrical Engineering, Stanford University, Stanford, CA 94305 Department of Bioengineering, Stanford University, Stanford, CA 94305 Department of Neurobiology, Stanford University, Stanford, CA 94305 Cold Sp...
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ژورنال
عنوان ژورنال: Behavioral Neuroscience
سال: 2011
ISSN: 1939-0084,0735-7044
DOI: 10.1037/a0022892